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您现在的位置:首页 >> 产品中心 >> 生化试剂、抗体、血清 >> 抗体/蛋白 >> Pierce抗体 20398Thermo抗体代理IL-33 Polyclonal Antibody Pierce抗体供应

Thermo抗体代理IL-33 Polyclonal Antibody Pierce抗体供应

  • 更新时间:  2023-07-25
  • 产品型号:  Pierce抗体 20398
  • 简单描述
  • hermo抗体代理IL-33 Polyclonal Antibody Pierce抗体供应
    Host / Isotype:
    RabbitClass:
    Polyclonal
    Type:
    Antibody
    Species Reactivity:
    Human (Hu) Murine (Ms) Rat
    WB
详细介绍

hermo抗体代理IL-33 Polyclonal Antibody Pierce抗体供应

IL-33 Polyclonal Antibody

View printable datasheet for IL-33 Polyclonal Antibody

Printable Datasheet

 

View 1 Product Image

View 1 Product Image

IL-33 Antibody for Western blot

>> See 3 other antibodies for IL33

Entrez Gene ID:

(Human) 90865

UniProt ID:

O95760

 

Details
Host / Isotype:Rabbit
Class:Polyclonal
Type:Antibody
Species Reactivity:Human (Hu) Murine (Ms) Rat (Rt)
Immunogen:A 19 amino acid peptide from near the center of human IL-33.
Ordering Information
Pierce IL-33 Polyclonal Antibody
Product NumberPkg. SizePricePurchase
PA5-20398100 ugPurchase »


Storage:Stored at -20ºC, avoid repeated freeze thaw cycles
Form:100 ug of affinity chromatography purified antibody (1 mg/ml) in PBS containing 0.02% sodium azide.



 

ApplicationsDilution *
Western Blot (WB)1 ug/ml

* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

 

Product Specific Information
PA5-20398 targets IL-33 in WB applications and shows reactivity with Human, Murine, and Rat samples.

The PA5-20398 immunogen is a 19 amino acid peptide from near the center of human IL-33.
General Information
Interleukin-33 (IL-33) is a recently identified member of the IL-1 family of cytokines whose other members include IL-1-a/beta, IL-1Ra and IL-18. Its receptor has been shown to be ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and IL-1R accessory protein (IL-1RAcP). Receptor binding of IL-33 activates NF-kappa-B and MAP kinases and induces the expression of TH2-associated cytokines such as IL-4, IL-5 and IL-6. Prolonged IL-33 treatment of mice led to the development of eosinophilia, splenomegaly, and severe pathological changes in mucosal organs such as lungs, esophagus and small intestine. Recent experiments have shown that IL-33 can also co-localize with heterochromatin and possesses transcriptional repressor activities, indicating that IL-33 may function as both a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties.

 

Product Images

Filter : All ApplicationsWB (1 imgs)

 

  • WB using PA5-20398

    Western Blot with anti-IL-33 Polyclonal Antibody (PA5-20398)

    Western Blot with anti-IL-33 Polyclonal Antibody (PA5-20398)

    View Product Details >>

    Western blot analysis of IL-33 in human lymph node tissue lysate with IL-33 antibody at (A) 1 and (B) 2 ug/mL.

    ... more >>

     

  • WB using PA5-20398

    Western Blot with anti-IL-33 Polyclonal Antibody (PA5-20398)

    Western Blot with anti-IL-33 Polyclonal Antibody (PA5-20398)

    View Product Details >>

    Western blot analysis of IL-33 in human lymph node tissue lysate with IL-33 antibody at (A) 1 and (B) 2 ug/mL.

    ... more >>

     

 

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